Open Access Articles- Top Results for Nedocromil


Structural formula of nedocromil
Space-filling model of the nedocromil molecule
Systematic (IUPAC) name
9-ethyl-4,6-dioxo-10-propyl-6,9-dihydro-4H-pyrano[3,2-g]quinoline-2,8-dicarboxylic acid
Clinical data
Trade names Alocril
AHFS/ monograph
MedlinePlus a601243
Inhalation and eye drops
Pharmacokinetic data
Protein binding 89%
Metabolism not metabolized
Half-life ~3.3 hours
Excretion excreted unchanged
69049-73-6 7pxY
R01AC07 R03BC03, S01GX04
PubChem CID 50294
DrugBank DB00716 7pxY
ChemSpider 45608 7pxY
UNII 0B535E0BN0 7pxY
KEGG D05129 7pxY
ChEBI CHEBI:7492 7pxY
Chemical data
Formula C19H17NO7
371.341 g/mol
 14pxY (what is this?)  (verify)

Nedocromil sodium is a medication considered as mast cell stabilizer which act to prevent wheezing, shortness of breath, and other breathing problems caused by asthma. It is administered by an inhaler under the brand name Tilade (although its effects in this form are far less than those in albuterol or other well-known inhaler medications) and as an eye drop under the brand name Alocril.[1][2] Liquid preparations are available in the UK under the name Rapitil for use for allergic eye reactions.[3]

Nedocromil is classified as a cromone. Nedocromil acts as a mast cell stabilizer, inhibits the degranulation of mast cells, prevents release of histamine and tryptase, so preventing the synthesis of prostaglandins and leukotrienes. US Production of inhaled nedocromil ceased in April 2008.[4]


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