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Open Access Articles- Top Results for Nerisopam

Nerisopam

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Nerisopam
180px
Systematic (IUPAC) name
4-(7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepin-1-yl)aniline
Clinical data
Identifiers
102771-12-0 7pxY
None
PubChem CID 65875
ChemSpider 59284 7pxY
UNII 18Q4O339AG 7pxY
ChEMBL CHEMBL2104732 7pxN
Chemical data
Formula C18H19N3O2
309.36
 14pxN (what is this?)  (verify)

Nerisopam (GYKI-52322) is a drug which is a 2,3-benzodiazepine derivative, related to tofisopam. It has potent anxiolytic and neuroleptic effects in animal studies.[1][2][3]

See also

References

  1. ^ Horváth K, Andrási F, Berzsenyi P, Pátfalusi M, Patthy M, Szabó G, Sebestyén L, Bagdy E, Körösi J, Botka P. A new psychoactive 5H-2,3-benzodiazepine with a unique spectrum of activity. Arzneimittelforschung. 1989 Aug;39(8):894-9.
  2. ^ Horváth K, Andrási F, Botka P, Hámori T. Anxiolytic profile of girisopam and GYKI 52,322 (EGIS 6775). Comparison with chlordiazepoxide and buspirone. Acta Physiologica Hungarica. 1992;79(2):153-61.
  3. ^ Palkovits M, Baffi JS, Berzsenyi P, Horváth EJ. Anxiolytic homophthalazines increase Fos-like immunoreactivity in selected brain areas of the rat. European Journal of Pharmacology. 1997 Jul 16;331(1):53-63.



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