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Open Access Articles- Top Results for Nitecapone

Nitecapone

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Nitecapone
File:Nitecapone.svg
Systematic (IUPAC) name
3-(3,4-dihydroxy-5-nitrobenzylidene)-2,4-pentanedione
Clinical data
Identifiers
116313-94-1
None
PubChem CID 5464105
ChemSpider 4576539
Chemical data
Formula C12H11NO6
265.219 g/mol

Nitecapone (INN; OR-462) is a drug which acts as a selective inhibitor of the enzyme catechol O-methyl transferase (COMT).[1][2] It was patented as an antiparkinsonian agent but was never marketed.[1]

See also

References

  1. ^ a b F.. Macdonald (1997). Dictionary of Pharmacological Agents. CRC Press. p. 1635. ISBN 978-0-412-46630-4. Retrieved 20 May 2012. 
  2. ^ Nissinen E, Lindén IB, Schultz E, Kaakkola S, Männistö PT, Pohto P (August 1988). "Inhibition of catechol-O-methyltransferase activity by two novel disubstituted catechols in the rat". European Journal of Pharmacology 153 (2-3): 263–9. PMID 3181288. doi:10.1016/0014-2999(88)90614-0. 


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