Open Access Articles- Top Results for O-806


Systematic (IUPAC) name
Clinical data
PubChem CID 10549140
ChemSpider 26001356 7pxY
Chemical data
Formula C22H27BrO2
403.352 g/mol
 14pxY (what is this?)  (verify)

O-806 is a drug which is a cannabinoid derivative that is used in scientific research. It is described as a mixed agonist/antagonist at the cannabinoid receptor CB1, meaning that it acts as an antagonist when co-administered alongside a more potent CB1 agonist, but exhibits weak partial agonist effects when administered by itself.[1][2]


  1. ^ Griffin, G.; Wray, E.; Rorrer, W.; Crocker, P.; Ryan, W.; Saha, B.; Razdan, R.; Martin, B.; Abood, M. (1999). "An investigation into the structural determinants of cannabinoid receptor ligand efficacy". British Journal of Pharmacology 126 (7): 1575–1584. PMC 1565939. PMID 10323589. doi:10.1038/sj.bjp.0702469.  edit
  2. ^ Griffin, G.; Wray, E.; Martin, B.; Abood, M. (1999). "Cannabinoid agonists and antagonists discriminated by receptor binding in rat cerebellum". British Journal of Pharmacology 128 (3): 684–688. PMC 1571656. PMID 10516649. doi:10.1038/sj.bjp.0702806.  edit

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