Ophiasis is a form of alopecia areata characterized by the loss of hair in the shape of a wave at the circumference of the head.
It gets its name from "ophis", which is the Greek word for snake, because of the apparent similarity to a snake-shape and the pattern of hair loss.
The term "sisaipho" is used to characterize the inverse pattern. Sisaipho is the reverse spelling of ophiasis. It is also called "ophiasis inversus".
Ophiasis has poor prognostic significance.