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Oportuzumab monatox

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Oportuzumab monatox?
Monoclonal antibody
Type Single-chain variable fragment
Source Humanized
Target EpCAM
Clinical data
Identifiers
945228-48-8 7pxN
None
Chemical data
Formula C3072H4723N877O952S12
69.6 kDa
 14pxN (what is this?)  (verify)

Oportuzumab monatox (proposed INN) is an antineoplastic. Chemically, oportuzumab it is a single chain variable fragment of a monoclonal antibody which binds to epithelial cell adhesion molecule (EpCAM, the tumor-associated calcium signal transducer 1). Oportuzumab is fused with Pseudomonas aeruginosa exotoxin A (which is reflected by the monatox in the drug's name).[1]

References

  1. ^ International Nonproprietary Names for Pharmaceutical Substances (INN, prepublication copy), World Health Organization.


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