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Open Access Articles- Top Results for Orotidine 5%27-monophosphate

Orotidine 5'-monophosphate

Orotidine 5'-monophosphate
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IUPAC name
3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-​(phosphonooxymethyl)oxolan-2-yl]​-2,6-dioxo-pyrimidine-4-carboxylic acid
Other names
Orotidylic acid,
OMP
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2149-82-8
Jmol-3D images Image
MeSH Orotidine+5'-monophosphate
PubChem Template:Chembox PubChem/format
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C10H13N2O11P
Molar mass 368.191 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Orotidine 5'-monophosphate (OMP), also known as orotidylic acid, is a pyrimidine nucleotide which is the last intermediate in the biosynthesis of uridine monophosphate. OMP is formed from orotate and phosphoribosyl pyrophosphate by the enzyme Orotate phosphoribosyltransferase

In humans, the enzyme UMP synthase converts OMP into uridine 5'- monophosphate. If UMP synthase is defective, orotic aciduria can result.

Template:Nucleotide metabolism intermediates

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