Adverts

Open Access Articles- Top Results for Oxypertine

Oxypertine

</th></tr>
Oxypertine
File:Oxypertine.png
Systematic (IUPAC) name
5,6-dimethoxy-2-methyl-3-[2-(4-phenylpiperazin-1-yl)ethyl]-1H-indole
Clinical data
AHFS/Drugs.com International Drug Names
  • (Prescription only)
Oral
Identifiers
153-87-7 7pxY
N05AE01
PubChem CID 4640
ChemSpider 4479
UNII 5JGL4G25R7 7pxY
KEGG D01219 7pxY
Chemical data
Formula C23H29N3O2
379.49 g/mol
 14pxY (what is this?)  (verify)

Oxypertine (Equipertine, Forit, Integrin, Lanturil, Lotawin, Opertil) is an antipsychotic used in the treatment of schizophrenia.[1] Chemically, it is an indole derivative similarly to molindone and a member of the phenylpiperazine class.[2] Like reserpine and tetrabenazine, oxypertine depletes catecholamines, though not serotonin, possibly underlying its neuroleptic efficacy.[3]

References

  1. ^ Hall, Chapman and; Rhodes, P. H (1996). Dictionary of organic compounds. London: Chapman & Hall. ISBN 0-412-54090-8. 
  2. ^ Breulet M, Labar P, Delree C, Collard J, Bobon J (February 1968). "[Oxypertine, peperazine derivative of tryptophan with neuroleptic and dynamogenic properties]". Acta Neurol Psychiatr Belg (in French) 68 (2): 116–27. PMID 4972600. 
  3. ^ Bak IJ, Hassler R, Kim JS (1969). "Differential monoamine depletion by oxypertine in nerve terminals. Granulated synaptic vesicles in relation to depletion of norepinephrine, dopamine and serotonin". Zeitschrift Für Zellforschung Und Mikroskopische Anatomie (Vienna, Austria : 1948) 101 (3): 448–62. PMID 5362847. 



Lua error in package.lua at line 80: module 'Module:Buffer' not found.