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P2RY14

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Identifiers
SymbolsP2RY14 ; BPR105; GPR105; P2Y14
External IDsOMIM610116 MGI2155705 HomoloGene15769 IUPHAR: 330 ChEMBL: 4518 GeneCards: P2RY14 Gene
RNA expression pattern
File:PBB GE P2RY14 206637 at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez9934140795
EnsemblENSG00000174944ENSMUSG00000036381
UniProtQ15391Q9ESG6
RefSeq (mRNA)NM_001081455NM_001008497
RefSeq (protein)NP_001074924NP_001008497
Location (UCSC)Chr 3:
150.93 – 151 Mb
Chr 3:
59.11 – 59.13 Mb
PubMed search[1][2]

P2Y purinoceptor 14 is a protein that in humans is encoded by the P2RY14 gene.[1]

The product of this gene, P2Y14 belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. This receptor is a P2Y purinergic receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene.[1]

See also

References

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.


External links

  • "P2Y Receptors: P2Y14". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. 


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