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Open Access Articles- Top Results for PBX1

PBX1

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Identifiers
SymbolsPBX1 ; DKFZp686B09108; MGC126627
External IDsOMIM176310 MGI97495 HomoloGene20574 ChEMBL: 4587 GeneCards: PBX1 Gene
RNA expression pattern
File:PBB GE PBX1 205253 at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez508718514
EnsemblENSG00000185630ENSMUSG00000052534
UniProtP40424P41778
RefSeq (mRNA)NM_001204961NM_001291508
RefSeq (protein)NP_001191890NP_001278437
Location (UCSC)Chr 1:
164.56 – 164.9 Mb
Chr 1:
168.12 – 168.43 Mb
PubMed search[1][2]

Pre-B-cell leukemia transcription factor 1 is a protein that in humans is encoded by the PBX1 gene.[1]


Interactions

PBX1 has been shown to interact with HOXB1,[2][3] MEIS1[4][5][6] and HOXB7.[7]

References

  1. ^ "Entrez Gene: PBX1 Pre-B-cell leukemia homeobox 1". 
  2. ^ Berthelsen, J; Zappavigna V; Ferretti E; Mavilio F; Blasi F (Mar 1998). "The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity". EMBO J. (ENGLAND) 17 (5): 1434–45. ISSN 0261-4189. PMC 1170491. PMID 9482740. doi:10.1093/emboj/17.5.1434. 
  3. ^ Piper, D E; Batchelor A H; Chang C P; Cleary M L; Wolberger C (Feb 1999). "Structure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and a fourth homeodomain helix in complex formation". Cell (UNITED STATES) 96 (4): 587–97. ISSN 0092-8674. PMID 10052460. doi:10.1016/S0092-8674(00)80662-5. 
  4. ^ Shen, W F; Rozenfeld S; Kwong A; Köm ves L G; Lawrence H J; Largman C (Apr 1999). "HOXA9 Forms Triple Complexes with PBX2 and MEIS1 in Myeloid Cells". Mol. Cell. Biol. (UNITED STATES) 19 (4): 3051–61. ISSN 0270-7306. PMC 84099. PMID 10082572. 
  5. ^ Shanmugam, K; Green N C; Rambaldi I; Saragovi H U; Featherstone M S (Nov 1999). "PBX and MEIS as Non-DNA-Binding Partners in Trimeric Complexes with HOX Proteins". Mol. Cell. Biol. (UNITED STATES) 19 (11): 7577–88. ISSN 0270-7306. PMC 84774. PMID 10523646. 
  6. ^ Jacobs, Y; Schnabel C A; Cleary M L (Jul 1999). "Trimeric Association of Hox and TALE Homeodomain Proteins Mediates Hoxb2 Hindbrain Enhancer Activity". Mol. Cell. Biol. (UNITED STATES) 19 (7): 5134–42. ISSN 0270-7306. PMC 84356. PMID 10373562. 
  7. ^ Chang, C P; Shen W F; Rozenfeld S; Lawrence H J; Largman C; Cleary M L (Mar 1995). "Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins". Genes Dev. (UNITED STATES) 9 (6): 663–74. ISSN 0890-9369. PMID 7729685. doi:10.1101/gad.9.6.663. 

Further reading

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External links


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