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Open Access Articles- Top Results for PCDH1

PCDH1

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Identifiers
SymbolsPCDH1 ; PC42; PCDH42
External IDsOMIM603626 MGI104692 HomoloGene12613 GeneCards: PCDH1 Gene
RNA expression pattern
File:PBB GE PCDH1 215277 at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez509775599
EnsemblENSG00000156453ENSMUSG00000051375
UniProtQ08174Q8CFX3
RefSeq (mRNA)NM_001278613NM_029357
RefSeq (protein)NP_001265542NP_083633
Location (UCSC)Chr 5:
141.23 – 141.26 Mb
Chr 18:
38.19 – 38.21 Mb
PubMed search[1][2]

Protocadherin-1 is a protein that in humans is encoded by the PCDH1 gene.[1][2]

This gene belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracellular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene.[2]

References

  1. ^ Sano K, Tanihara H, Heimark RL, Obata S, Davidson M, St John T, Taketani S, Suzuki S (Jul 1993). "Protocadherins: a large family of cadherin-related molecules in central nervous system". EMBO J 12 (6): 2249–56. PMC 413453. PMID 8508762. 
  2. ^ a b "Entrez Gene: PCDH1 protocadherin 1". 

Further reading

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