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POU4F2

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Identifiers
SymbolsPOU4F2 ; BRN3.2; BRN3B; Brn-3b
External IDsOMIM113725 MGI102524 HomoloGene20959 GeneCards: POU4F2 Gene
RNA expression pattern
File:PBB GE POU4F2 207725 at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez545818997
EnsemblENSG00000151615ENSMUSG00000031688
UniProtQ12837Q63934
RefSeq (mRNA)NM_004575NM_138944
RefSeq (protein)NP_004566NP_620394
Location (UCSC)Chr 4:
147.56 – 147.56 Mb
Chr 8:
78.43 – 78.44 Mb
PubMed search[1][2]

POU domain, class 4, transcription factor 2 is a protein that in humans is encoded by the POU4F2 gene.[1][2]

POU4F2 is a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. A class IV POU-domain protein, POU4F2 is found in human retina exclusively within a subpopulation of ganglion cells where it may play a role in determining or maintaining the identities of a small subset of visual system neurons.[supplied by OMIM][2]

Interactions

POU4F2 has been shown to interact with Estrogen receptor alpha.[3]

See also

References

Further reading

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External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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