Open Access Articles- Top Results for Periosteum


File:607 Periosteum and Endosteum.jpg
The periosteum covers the outside of bones.
Meninges of the CNS
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Anatomical terminology

Periosteum (from Greek περί (peri 'around') and ὀστοῦν(ostoun 'bone')) is a membrane that covers the outer surface of all bones,[1] except at the joints of long bones.[nb 1] Endosteum lines the inner surface of all bones.


File:624 Diagram of Compact Bone-new.jpg
The periosteum consists of an inner osteogenic layer and an outer fibrous layer
Periosteum consists of dense irregular connective tissue. Periosteum is divided into an outer "fibrous layer" and inner "cambium layer" (or "osteogenic layer"). The fibrous layer contains fibroblasts, while the cambium layer contains progenitor cells that develop into osteoblasts. These osteoblasts are responsible for increasing the width of a long bone[nb 2] and the overall size of the other bone types. After a bone fracture the progenitor cells develop into osteoblasts and chondroblasts, which are essential to the healing process.

As opposed to osseous tissue, periosteum has nociceptive nerve endings, making it very sensitive to manipulation. It also provides nourishment by providing the blood supply to the body from the marrow.[2] Periosteum is attached to bone by strong collagenous fibers called Sharpey's fibres, which extend to the outer circumferential and interstitial lamellae. It also provides an attachment for muscles and tendons.

Periosteum that covers the outer surface of the bones of the skull is known as "pericranium" except when in reference to the layers of the scalp.



The word Periosteum is derived from the Greek Peri- meaning "surrounding" and -osteon, meaning "bone". The Peri refers to the fact that the Periosteum is the outermost layer of long bones, surrounding other inner layers.[3]

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See also


  1. ^ At the joints of long bones the bone's outer surface is lined with "articular cartilage", a type of hyaline cartilage.
  2. ^ The length of a long bone is controlled by the epiphyseal plate.


  1. ^ Netter, Frank H.; Dingle, Regina V.; Mankin, Henry J. (1990). Musculoskeletal system: anatomy, physiology, and metabolic disorders. Summit, New Jersey: Ciba-Geigy Corporation. p. 170. ISBN 0-914168-88-6. 
  2. ^ Modric, Jan. "Periosteum". eHealthStar. Retrieved 10 July 2014. 
  3. ^ "peri-". Online Etymology Dictionary. Retrieved 7 July 2013. 


  • Brighton, Carl T. and Robert M. Hunt (1997), "Early histologic and ultrastructural changes in microvessels of periosteal callus", Journal of Orthopaedic Trauma, 11 (4): 244-253

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