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Phenylethylidenehydrazine

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Phenylethylidenehydrazine
File:Phenylethylidenehydrazine.svg
Systematic (IUPAC) name
(1E)-(2-Phenylethylidene)hydrazine
Clinical data
  • Uncontrolled
Pharmacokinetic data
Half-life ~12 hours
Identifiers
29443-41-2
None
PubChem CID 10103216
ChemSpider 8278744
Chemical data
Formula C8H10N2
134.18 g/mol

Phenylethylidenehydrazine (PEH), also known as 2-phenylethylhydrazone, is an inhibitor of the enzyme GABA transaminase (GABA-T).[1][2] It is a metabolite of the antidepressant phenelzine and is responsible for its elevation of GABA concentrations.[1] PEH likely plays a significant role in phenelzine's high efficacy in treating anxiety disorders.

See also

References