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Open Access Articles- Top Results for Pipoxizine

Pipoxizine

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Pipoxizine
File:Pipoxizine.svg
Systematic (IUPAC) name
2-(2-{2-[4-(Diphenylmethylene)-1-piperidinyl]ethoxy}ethoxy)ethanol
Clinical data
Identifiers
55837-21-3
None
PubChem CID 68750
ChemSpider 61995
Chemical data
Formula C24H31NO3
381.508 g/mol

Pipoxizine (INN) is an first-generation antihistamine as well as serotonin antagonist which is closely related structurally to antihistamines of the diphenylmethane/piperazine family.[1][2] It was investigated as a bronchodilator but was never marketed.[1][3][4]

See also

References

  1. ^ a b C.R. Ganellin; David J. Triggle (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. pp. 1619–. ISBN 978-0-412-46630-4. 
  2. ^ World Health Organization (1988). International Nonproprietary Names (INN) for Pharmaceutical Substances. W.H.O. 
  3. ^ Brunner A, Gartmann J, Studler H. "Pipoxizine, a New Bronchodilator". Lung 154 (2): 143. 
  4. ^ Neukirch F, Korobaeff M, Verdier F, Timsit G, Fay M, Drutel P (1978). "[Effect of a histamine aerosol in 20 subjects with histamine hyperreactivity. Application to a study of the protective properties of pipoxizine]". Rev Inst Hyg Mines (Hasselt) (in French) 33 (4): 191–5. PMID 45187. 



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