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Open Access Articles- Top Results for Procaterol

Procaterol

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Procaterol
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Systematic (IUPAC) name
(±)-(1R,2S)-rel-8-Hydroxy-5-[1-hydroxy-2-(isopropylamino)butyl]-quinolin-2(1H)-one
Clinical data
AHFS/Drugs.com Micromedex Detailed Consumer Information
Oral, inhalation
Identifiers
59828-07-8 7pxY
R03AC16 R03CC08
PubChem CID 4916
ChemSpider 599984 7pxN
UNII X7I3EMM5K0 7pxY
KEGG D08424 7pxY
Chemical data
Formula C16H22N2O3
290.357 g/mol
 14pxN (what is this?)  (verify)

Procaterol, applied as procaterol hydrochloride (USAN), is an intermediate-acting β2-adrenergic receptor agonist used for the treatment of asthma. It has never been filed for FDA evaluation in the United States, where it is not marketed. The drug is readily oxidised in the presence of moisture and air, making it unsuitable for therapeutic use by inhalation.[1] Pharmaceutical company Parke-Davis/Warner-Lambert researched a stabilizer to prevent oxidation, but an effective one was never developed.[1]

References

  1. 1.0 1.1 US 4616022, Ghebre-sellassie, Issac & Russell U. Nesbitt Jr., "Procaterol stabilization", published 1984, issued 1986 


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