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Open Access Articles- Top Results for Promazine

Journal of Clinical & Experimental Ophthalmology
Corneal Manifestations of Chronic Systemic Drug Therapy

Promazine

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Promazine
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Systematic (IUPAC) name
N,N-dimethyl-3-(10H-phenothiazin-10-yl)-propan-1-amine
Clinical data
AHFS/Drugs.com Micromedex Detailed Consumer Information
MedlinePlus a600010
Pharmacokinetic data
Protein binding 94%
Identifiers
58-40-2 7pxY
N05AA03
PubChem CID 4926
DrugBank DB00420 7pxY
ChemSpider 4757 7pxY
UNII O9M39HTM5W 7pxY
ChEBI CHEBI:8459 7pxY
ChEMBL CHEMBL564 7pxY
Chemical data
Formula C17H20N2S
284.42 g/mol
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Promazine (Sparine) is a medication that belongs to the phenothiazine class of antipsychotics. An older medication used to treat schizophrenia, it is still prescribed, alongside newer agents such as olanzapine and quetiapine. It has predominantly anticholinergic side effects, though extrapyramidal side effects are not uncommon either.

Promazine is not approved for human use in the United States. It is available in the US for veterinary use under the names Promazine and Tranquazine.


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