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Quinazolinone

4-Quinazolinone
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IUPAC name
Quinazolin-4(3H)-one
Other names
4(3H)-Quinazolinone; 4(1H)-Quinazolinone; 3,4-Dihydroquinazolin-4-one; 4(3H)-Quinazolone; 4-Hydroxyquinazoline; 4-Oxo-3,4-dihydroquinazoline; 4-Oxoquinazoline; 4-Quinazolinol; 4-Quinazolinone; 4-Quinazolone
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491-36-1
ChEMBL ChEMBL266540
ChemSpider 56797
Jmol-3D images Image
PubChem Template:Chembox PubChem/format
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C8H6N2O
Molar mass Lua error in Module:Math at line 495: attempt to index field 'ParserFunctions' (a nil value). g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Quinazolinone is a heterocyclic chemical compound. There are two structural isomers, 2-quinazolinone and 4-quinazolinone, with the 4-isomer being the more common.

Derivatives

Quinazolinones are also a class of drugs which function as hypnotic/sedatives that contain a 4-quinazolinone core. Their use has also been proposed in the treatment of cancer.[1] Examples include afloqualone, cloroqualone, and diproqualone.

Other pharmaceuticals containing the quinazolinone group include raltitrexed, zenarestat, fenquizone, quinethazone, and metolazone.

Alkaloids containing the quinazolinone core include evodiamine, febrifugine, and halofuginone.

References