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RHOBTB1

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Identifiers
SymbolsRHOBTB1 ; KIAA0740; MGC33059; MGC33841
External IDsOMIM607351 MGI1916538 HomoloGene8892 GeneCards: RHOBTB1 Gene
RNA expression pattern
File:PBB GE RHOBTB1 212651 at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez988669288
EnsemblENSG00000072422ENSMUSG00000019944
UniProtO94844Q9DAK3
RefSeq (mRNA)NM_001242359NM_001081347
RefSeq (protein)NP_001229288NP_001074816
Location (UCSC)Chr 10:
62.63 – 62.76 Mb
Chr 10:
69.15 – 69.29 Mb
PubMed search[1][2]

Rho-related BTB domain-containing protein 1 is a protein that in humans is encoded by the RHOBTB1 gene.[1][2]

The protein encoded by this gene belongs to the Rho family of the Ras superfamily of small GTPases. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate transcriptional splice variants have been characterized.[2]

References

  1. ^ Rivero F, Dislich H, Glockner G, Noegel AA (Mar 2001). "The Dictyostelium discoideum family of Rho-related proteins". Nucleic Acids Res 29 (5): 1068–79. PMC 29714. PMID 11222756. doi:10.1093/nar/29.5.1068. 
  2. ^ a b "Entrez Gene: RHOBTB1 Rho-related BTB domain containing 1". 

Further reading

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