Open Access Articles- Top Results for RPS6KA5


SymbolsRPS6KA5 ; MSK1; MSPK1; RLPK
External IDsOMIM603607 MGI1920336 HomoloGene48302 IUPHAR: 1523 ChEMBL: 4237 GeneCards: RPS6KA5 Gene
EC number2.7.11.1
RNA expression pattern
File:PBB GE RPS6KA5 204635 at tn.png
File:PBB GE RPS6KA5 204633 s at tn.png
More reference expression data
RefSeq (mRNA)NM_004755NM_153587
RefSeq (protein)NP_004746NP_705815
Location (UCSC)Chr 14:
91.34 – 91.53 Mb
Chr 12:
100.55 – 100.73 Mb
PubMed search[1][2]

Ribosomal protein S6 kinase alpha-5 is an enzyme that in humans is encoded by the RPS6KA5 gene.[1][2][3]


RPS6KA5 has been shown to interact with CREB1.[1][4]


  1. 1.0 1.1 Deak M, Clifton AD, Lucocq LM, Alessi DR (September 1998). "Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB". EMBO J 17 (15): 4426–41. PMC 1170775. PMID 9687510. doi:10.1093/emboj/17.15.4426. 
  2. Jiang C, Yu L, Tu Q, Zhao Y, Zhang H, Zhao S (April 2000). "Assignment of a member of the ribosomal protein S6 kinase family, RPS6KA5, to human chromosome 14q31→q32.1 by radiation hybrid mapping". Cytogenet Cell Genet 87 (3–4): 261–2. PMID 10702687. doi:10.1159/000015441. 
  3. "Entrez Gene: RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5". 
  4. Wang, X; Li W; Williams M; Terada N; Alessi D R; Proud C G (August 2001). "Regulation of elongation factor 2 kinase by p90RSK1 and p70 S6 kinase". EMBO J. (England) 20 (16): 4370–9. ISSN 0261-4189. PMC 125559. PMID 11500364. doi:10.1093/emboj/20.16.4370. 

Further reading


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