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Radequinil
File:Radequinil.svg | |
Systematic (IUPAC) name | |
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5-(3-methoxyphenyl)-3-(5-methyl-1,2,4-oxadiazol-3-yl)-1,6-naphthyridin-2(1H)-one | |
Clinical data | |
Identifiers | |
219846-31-8 | |
None | |
PubChem | CID 22714308 |
ChemSpider | 11584471 |
Chemical data | |
Formula | C18H14N4O3 |
334.329 g/mol | |
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Radequinil (INN; AC-3933) is a cognitive enhancer which acts as a partial inverse agonist of the benzodiazepine site of the GABAA receptor.[1] It was under development by Dainippon Sumitomo Pharma for the treatment of Alzheimer's disease and made it to phase II clinical trials but development seems to have been halted and it was never marketed.[1][2]
See also
References
- ^ a b Martocchia A, Falaschi P (2008). "Current Strategies of Therapy in Alzheimer’s Disease" (PDF). The Open Neuropsychopharmacology Journal 1: 19–23.
- ^ Pogacic, Vanda; Herling, Paul (2007). "List of Drugs in Development for Neurodegenerative Diseases". Neurodegenerative Diseases 4 (6): 443486. ISSN 1660-2862. doi:10.1159/000107705.
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