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Open Access Articles- Top Results for Reposal

Reposal

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Reposal
File:Reposal.svg
Systematic (IUPAC) name
5-bicyclo[3.2.1]oct-2-en-3-yl-5-ethylpyrimidine-2,4,6(1H,3H,5H)-trione
Clinical data
Identifiers
3625-25-0 7pxN
N05CA12
PubChem CID 19254
ChemSpider 10468690 7pxY
ChEMBL CHEMBL505851 7pxN
Synonyms Reposal, 5-Ethyl-5-(bicyclo(3.2.1)octenyl)barbituric acid
Chemical data
Formula C14H18N2O3
262.304 g/mol
 14pxN (what is this?)  (verify)

Reposal is a barbiturate derivative invented in the 1960s in Denmark. It has sedative, hypnotic and anticonvulsant properties, and was used primarily for the treatment of insomnia.[1][2][3]

References

  1. Kessing, S. V.; Tarding, F.; Thomsen, A. C. (1963). "Reposal, A New Hypnotic. I. Pharmacodynamic Activity". Ugeskrift for laeger (in Danish) 125: 1735–1738. PMID 14103836.  edit
  2. Kessing, S. V.; Tarding, F.; Thomsen, A. C. (1963). "Reposal, A New Hypnotic. II. Clinical Effects". Ugeskrift for laeger (in Danish) 125: 1739–1741. PMID 14103837.  edit
  3. Nielsen, P.; Tarding, F. (1968). "The metabolic fate of 5-(bicyclo-3,2,1,-oct-2-en-2-yl)-5-ethyl barbituric acid, (Reposal)". Acta pharmacologica et toxicologica 26 (6): 521–530. PMID 5756387. doi:10.1111/j.1600-0773.1968.tb00471.x.  edit



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