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SEMA7A

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Identifiers
SymbolsSEMA7A ; CD108; CDw108; H-SEMA-K1; H-Sema-L; JMH; SEMAK1; SEMAL
External IDsOMIM607961 MGI1306826 HomoloGene2678 GeneCards: SEMA7A Gene
RNA expression pattern
File:PBB GE SEMA7A 210083 at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez848220361
EnsemblENSG00000138623ENSMUSG00000038264
UniProtO75326Q9QUR8
RefSeq (mRNA)NM_001146029NM_011352
RefSeq (protein)NP_001139501NP_035482
Location (UCSC)Chr 15:
74.7 – 74.73 Mb
Chr 9:
57.94 – 57.96 Mb
PubMed search[1][2]

Semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) (SEMA7A) also known as CD108 (Cluster of Differentiation 108), is a human gene.[1]

SEMA7A is a membrane-bound semaphorin that associates with cell surfaces via a glycosylphosphatidylinositol (GPI) linkage. SEMA7A is also known as the John-Milton-Hagen (JMH) blood group antigen, an 80-kD glycoprotein expressed on activated lymphocytes and erythrocytes.[supplied by OMIM][1]

Genetics

This protein is known to have eight variants in the extracellular region: seven lie within the Sema domain and one within the PSI domain.

Molecular biology

This protein forms dimers.

Notes

This protein acts as a receptor for the malaria parasite Plasmodium falciparum.

See also

References

Further reading

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External links

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