Open Access Articles- Top Results for SIRPG


SymbolsSIRPG ; CD172g; SIRP-B2; SIRPB2; SIRPgamma; bA77C3.1
External IDsOMIM605466 HomoloGene56809 GeneCards: SIRPG Gene
RNA expression pattern
File:PBB GE SIRPG 220485 s at tn.png
More reference expression data
RefSeq (mRNA)NM_001039508n/a
RefSeq (protein)NP_001034597n/a
Location (UCSC)Chr 20:
1.61 – 1.64 Mb
PubMed search[1]n/a

Signal-regulatory protein gamma is a protein that in humans is encoded by the SIRPG gene.[1][2][3] SIRPG has also recently been designated CD172G (cluster of differentiation 172G).

The protein encoded by this gene is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Alternatively spliced transcript variants encoding different isoforms have been described.[3]


  1. ^ Ichigotani Y, Matsuda S, Machida K, Oshima K, Iwamoto T, Yamaki K, Hayakawa T, Hamaguchi M (Jan 2001). "Molecular cloning of a novel human gene (SIRP-B2) which encodes a new member of the SIRP/SHPS-1 protein family". J Hum Genet 45 (6): 378–82. PMID 11185750. doi:10.1007/s100380070013. 
  2. ^ van den Berg TK, van Beek EM, Buhring HJ, Colonna M, Hamaguchi M, Howard CJ, Kasuga M, Liu Y, Matozaki T, Neel BG, Parkos CA, Sano S, Vignery A, Vivier E, Wright M, Zawatzky R, Barclay AN (Dec 2005). "A nomenclature for signal regulatory protein family members". J Immunol 175 (12): 7788–9. PMID 16339511. doi:10.4049/jimmunol.175.12.7788. 
  3. ^ a b "Entrez Gene: SIRPG signal-regulatory protein gamma". 

Further reading


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