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Open Access Articles- Top Results for SLC22A7

SLC22A7

Template:Infobox3cols/rowTemplate:Infobox3cols/rowTemplate:Infobox3cols/rowTemplate:Infobox3cols/row
Identifiers
SymbolsSLC22A7 ; NLT; OAT2
External IDsOMIM604995 MGI1859559 HomoloGene21328 IUPHAR: 1026 GeneCards: SLC22A7 Gene
RNA expression pattern
File:PBB GE SLC22A7 220554 at tn.png
File:PBB GE SLC22A7 221661 at tn.png
File:PBB GE SLC22A7 221662 s at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez10864108114
EnsemblENSG00000137204ENSMUSG00000067144
UniProtQ9Y694Q91WU2
RefSeq (mRNA)NM_006672NM_144856
RefSeq (protein)NP_006663NP_659105
Location (UCSC)Chr 6:
43.26 – 43.27 Mb
Chr 17:
46.43 – 46.44 Mb
PubMed search[1][2]

Solute carrier family 22 member 7 is a protein that in humans is encoded by the SLC22A7 gene.[1][2][3]

The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Alternatively spliced transcript variants encoding different isoforms have been described.[3]

Interactive pathway map

Click on genes, proteins and metabolites below to link to respective articles. [§ 1]

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Fluorouracil (5-FU) Activity edit
  1. ^ The interactive pathway map can be edited at WikiPathways: "FluoropyrimidineActivity_WP1601". 

See also

References

  1. ^ Sekine T, Cha SH, Tsuda M, Apiwattanakul N, Nakajima N, Kanai Y, Endou H (Jul 1998). "Identification of multispecific organic anion transporter 2 expressed predominantly in the liver". FEBS Lett 429 (2): 179–82. PMID 9650585. doi:10.1016/S0014-5793(98)00585-7. 
  2. ^ Kok LD, Siu SS, Fung KP, Tsui SK, Lee CY, Waye MM (Jun 2000). "Assignment of liver-specific organic anion transporter (SLC22A7) to human chromosome 6 bands p21.2→p21.1 using radiation hybrids". Cytogenet Cell Genet 88 (1–2): 76–7. PMID 10773670. doi:10.1159/000015489. 
  3. ^ a b "Entrez Gene: SLC22A7 solute carrier family 22 (organic anion transporter), member 7". 

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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