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SLC2A7

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Identifiers
SymbolsSLC2A7 ; GLUT7
External IDsOMIM610371 MGI3650865 HomoloGene72470 IUPHAR: 881 GeneCards: SLC2A7 Gene
Orthologs
SpeciesHumanMouse
Entrez155184435818
EnsemblENSG00000197241ENSMUSG00000062064
UniProtQ6PXP3P0C6A1
RefSeq (mRNA)NM_207420NM_001085529
RefSeq (protein)NP_997303NP_001078998
Location (UCSC)Chr 1:
9.06 – 9.09 Mb
Chr 4:
150.15 – 150.17 Mb
PubMed search[1][2]

Solute carrier family 2, facilitated glucose transporter member 7 also known as glucose transporter 7 (GLUT7) is a protein that in humans is encoded by the SLC2A7 gene.[1][2]

SLC2A7 belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion.[2] This family of transporters shows conservation of 12 transmembrane helices as well as functionally significant amino acid residues.[3]

See also

References

  1. ^ "Entrez Gene: solute carrier family 2 (facilitated glucose transporter)". 
  2. ^ a b Li Q, Manolescu A, Ritzel M, Yao S, Slugoski M, Young JD, Chen XZ, Cheeseman CI (July 2004). "Cloning and functional characterization of the human GLUT7 isoform SLC2A7 from the small intestine". Am. J. Physiol. Gastrointest. Liver Physiol. 287 (1): G236–42. PMID 15033637. doi:10.1152/ajpgi.00396.2003. 
  3. ^ Joost HG, Thorens B (2001). "The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members (review)". Mol. Membr. Biol. 18 (4): 247–56. PMID 11780753. doi:10.1080/09687680110090456. 

Further reading

  • Manolescu A, Salas-Burgos AM, Fischbarg J, Cheeseman CI (2005). "Identification of a hydrophobic residue as a key determinant of fructose transport by the facilitative hexose transporter SLC2A7 (GLUT7).". J. Biol. Chem. 280 (52): 42978–83. PMID 16186102. doi:10.1074/jbc.M508678200. 
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