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Identifiers
Symbols	SLC32A1 ; VGAT; VIAAT
External IDs	MGI: 1194488 HomoloGene: 56451 IUPHAR: 1133 ChEMBL: 4536 GeneCards: SLC32A1 Gene
Gene ontology Molecular function • glycine transmembrane transporter activity • gamma-aminobutyric acid:proton symporter activity Cellular component • plasma membrane • integral component of membrane • dendrite • synaptic vesicle membrane • neuron projection • dendrite terminus • neuron projection terminus • cone cell pedicle • cell tip • inhibitory synapse • clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane Biological process • ion transport • synaptic transmission • neurotransmitter secretion • aging • gamma-aminobutyric acid transport • glycine transport • transmembrane transport Sources: Amigo / QuickGO
RNA expression pattern
File:PBB GE SLC32A1 gnf1h08592 at tn.png
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	140679	22348
Ensembl	ENSG00000101438	ENSMUSG00000037771
UniProt	Q9H598	O35633
RefSeq (mRNA)	NM_080552	NM_009508
RefSeq (protein)	NP_542119	NP_033534
Location (UCSC)	Chr 20: 37.35 – 37.36 Mb	Chr 2: 158.61 – 158.62 Mb
PubMed search	[1]	[2]

Vesicular inhibitory amino acid transporter is a protein that in humans is encoded by the SLC32A1 gene.

The protein encoded by this gene is an integral membrane protein involved in gamma-aminobutyric acid (GABA) and glycine uptake into synaptic vesicles. The encoded protein is a member of amino acid/polyamine transporter family II.

See also

• Solute carrier family

Further reading

• McIntire SL, Reimer RJ, Schuske K et al. (1997). "Identification and characterization of the vesicular GABA transporter". Nature 389 (6653): 870–6. PMID 9349821. doi:10.1038/39908.  CS1 maint: Explicit use of et al. (link)
• Kleiderlein JJ, Nisson PE, Jessee J et al. (1999). "CCG repeats in cDNAs from human brain". Hum. Genet. 103 (6): 666–73. PMID 9921901. doi:10.1007/s004390050889.  CS1 maint: Explicit use of et al. (link)
• Deloukas P, Matthews LH, Ashurst J et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature 414 (6866): 865–71. PMID 11780052. doi:10.1038/414865a.  CS1 maint: Explicit use of et al. (link)
• Chessler SD, Simonson WT, Sweet IR, Hammerle LP (2002). "Expression of the vesicular inhibitory amino acid transporter in pancreatic islet cells: distribution of the transporter within rat islets". Diabetes 51 (6): 1763–71. PMID 12031963. doi:10.2337/diabetes.51.6.1763. 
• Jellali A, Stussi-Garaud C, Gasnier B et al. (2002). "Cellular localization of the vesicular inhibitory amino acid transporter in the mouse and human retina". J. Comp. Neurol. 449 (1): 76–87. PMID 12115694. doi:10.1002/cne.10272.  CS1 maint: Explicit use of et al. (link)
• Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241. PMID 12477932. doi:10.1073/pnas.242603899.  CS1 maint: Explicit use of et al. (link)
• Geigerseder C, Doepner R, Thalhammer A et al. (2003). "Evidence for a GABAergic system in rodent and human testis: local GABA production and GABA receptors". Neuroendocrinology 77 (5): 314–23. PMID 12806177. doi:10.1159/000070897.  CS1 maint: Explicit use of et al. (link)
• Ota T, Suzuki Y, Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. PMID 14702039. doi:10.1038/ng1285.  CS1 maint: Explicit use of et al. (link)
• Gerhard DS, Wagner L, Feingold EA et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. PMC 528928. PMID 15489334. doi:10.1101/gr.2596504.  CS1 maint: Explicit use of et al. (link)

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