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SLC39A6

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Identifiers
SymbolsSLC39A6 ; LIV-1
External IDsOMIM608731 MGI2147279 HomoloGene8199 IUPHAR: 1185 GeneCards: SLC39A6 Gene
RNA expression pattern
File:PBB GE SLC39A6 202088 at tn.png
File:PBB GE SLC39A6 202089 s at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez25800106957
EnsemblENSG00000141424ENSMUSG00000024270
UniProtQ13433Q8C145
RefSeq (mRNA)NM_001099406NM_139143
RefSeq (protein)NP_001092876NP_631882
Location (UCSC)Chr 18:
33.69 – 33.71 Mb
Chr 18:
24.58 – 24.6 Mb
PubMed search[1][2]

Zinc transporter ZIP6 is a protein that in humans is encoded by the SLC39A6 gene.[1][2][3]

Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A6 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003).[supplied by OMIM][3]

See also

References

  1. ^ Taylor KM, Nicholson RI (Mar 2003). "The LZT proteins; the LIV-1 subfamily of zinc transporters". Biochim Biophys Acta 1611 (1–2): 16–30. PMID 12659941. doi:10.1016/S0005-2736(03)00048-8. 
  2. ^ Taylor KM, Morgan HE, Johnson A, Hadley LJ, Nicholson RI (Sep 2003). "Structure-function analysis of LIV-1, the breast cancer-associated protein that belongs to a new subfamily of zinc transporters". Biochem J 375 (Pt 1): 51–9. PMC 1223660. PMID 12839489. doi:10.1042/BJ20030478. 
  3. ^ a b "Entrez Gene: SLC39A6 solute carrier family 39 (zinc transporter), member 6". 

Further reading

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