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Open Access Articles- Top Results for SLC6A14

SLC6A14

Template:Infobox3cols/rowTemplate:Infobox3cols/rowTemplate:Infobox3cols/rowTemplate:Infobox3cols/row
Identifiers
SymbolsSLC6A14 ; BMIQ11
External IDsOMIM300444 MGI1890216 HomoloGene38290 IUPHAR: 937 GeneCards: SLC6A14 Gene
RNA expression pattern
File:PBB GE SLC6A14 219795 at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez1125456774
EnsemblENSG00000087916ENSMUSG00000031089
UniProtQ9UN76Q9JMA9
RefSeq (mRNA)NM_007231NM_020049
RefSeq (protein)NP_009162NP_064433
Location (UCSC)Chr HG1463_PATCH:
115.55 – 115.58 Mb
Chr X:
21.71 – 21.74 Mb
PubMed search[1][2]

Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) is a protein that in humans is encoded by the SLC6A14 gene.[1][2]

Function

SLC6A14 is a member of the Na(+)- and Cl(−)-dependent neurotransmitter transporter family and transports both neutral and cationic amino acids in an Na(+)- and Cl(−)-dependent manner.[supplied by OMIM][2]

References

  1. ^ Sloan JL, Mager S (Sep 1999). "Cloning and functional expression of a human Na(+) and Cl(−)-dependent neutral and cationic amino acid transporter B(0+)". J Biol Chem 274 (34): 23740–5. PMID 10446133. doi:10.1074/jbc.274.34.23740. 
  2. ^ a b "Entrez Gene: SLC6A14 solute carrier family 6 (amino acid transporter), member 14". 

Further reading

  • Ohman M, Oksanen L, Kaprio J, Koskenvuo M, Mustajoki P, Rissanen A et al. (2000). "Genome-wide scan of obesity in Finnish sibpairs reveals linkage to chromosome Xq24". J. Clin. Endocrinol. Metab. 85 (9): 3183–90. PMID 10999806. doi:10.1210/jc.85.9.3183. 
  • Sloan JL, Grubb BR, Mager S (2003). "Expression of the amino acid transporter ATB 0+ in lung: possible role in luminal protein removal". Am. J. Physiol. Lung Cell Mol. Physiol. 284 (1): L39–49. PMID 12388375. doi:10.1152/ajplung.00164.2002 (inactive 2015-01-01). 
  • Suviolahti E, Oksanen LJ, Ohman M, Cantor RM, Ridderstrale M, Tuomi T et al. (2004). "The SLC6A14 gene shows evidence of association with obesity". J. Clin. Invest. 112 (11): 1762–72. PMC 281637. PMID 14660752. doi:10.1172/JCI200317491. 
  • Durand E, Boutin P, Meyre D, Charles MA, Clement K, Dina C et al. (2004). "Polymorphisms in the amino acid transporter solute carrier family 6 (neurotransmitter transporter) member 14 gene contribute to polygenic obesity in French Caucasians". Diabetes 53 (9): 2483–6. PMID 15331564. doi:10.2337/diabetes.53.9.2483. 
  • Gupta N, Miyauchi S, Martindale RG, Herdman AV, Podolsky R, Miyake K et al. (2005). "Upregulation of the amino acid transporter ATB0,+ (SLC6A14) in colorectal cancer and metastasis in humans". Biochim. Biophys. Acta 1741 (1–2): 215–23. PMID 15905073. doi:10.1016/j.bbadis.2005.04.002. 
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