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Secnidazole

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Secnidazole
File:Secnidazole.svg
Systematic (IUPAC) name
1-(2-Methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol
Clinical data
AHFS/Drugs.com International Drug Names
Oral
Identifiers
3366-95-8 7pxN
P01AB07
PubChem CID 71815
ChemSpider 64839 7pxY
UNII R3459K699K 7pxY
KEGG D07353 7pxY
ChEMBL CHEMBL498847 7pxY
Synonyms PM 185184, RP 14539
Chemical data
Formula C7H11N3O3
185.180 g/mol
 14pxN (what is this?)  (verify)

Secnidazole (trade names Flagentyl, Sindose, Secnil) is a nitroimidazole anti-infective. Effectiveness in the treatment of dientamoebiasis has been reported.[1] It has also been tested against Atopobium vaginae.[2]

References

  1. ^ Girginkardeşler, N.; Coşkun, S.; Cüneyt Balcioğlu, I.; Ertan, P.; Ok, U. Z. (2003). "Dientamoeba fragilis, a neglected cause of diarrhea, successfully treated with secnidazole". Clinical Microbiology and Infection 9 (2): 110–113. PMID 12588330. doi:10.1046/j.1469-0691.2003.00504.x.  edit
  2. ^ De Backer, E.; Dubreuil, L.; Brauman, M.; Acar, J.; Vaneechoutte, M. (2009). "In vitro activity of secnidazole against Atopobium vaginae, an anaerobic pathogen involved in bacterial vaginosis". Clinical Microbiology and Infection 16 (5): 470–472. PMID 19548924. doi:10.1111/j.1469-0691.2009.02852.x.  edit

External links

  • Gillis, J. C.; Wiseman, L. R. (1996). "Secnidazole. A review of its antimicrobial activity, pharmacokinetic properties and therapeutic use in the management of protozoal infections and bacterial vaginosis". Drugs 51 (4): 621–38. PMID 8706597. 


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