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Sercloremine

Sercloremine
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IUPAC name
4-(5-Chloro-1-benzofuran-2-yl)-1-methylpiperidine
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54403-19-9 7pxY
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C14H16ClNO
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Sercloremine (CGP-4718A), usually as the hydrochloride salt, is a drug which was developed in the 1980s and was formerly under investigation as an antidepressant, but was never marketed.[1][2] It acts as a selective, reversible inhibitor of monoamine oxidase A (RIMA) and serotonin reuptake inhibitor.[1][3]

References

  1. ^ a b Barrie Hesp; Cain (2 September 1987). ANNUAL REPORTS IN MED CHEMISTRY V22 PPR. Academic Press. pp. 25–. ISBN 978-0-08-058366-2. 
  2. ^ C.R. Ganellin; David J. Triggle (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. pp. 1801–. ISBN 978-0-412-46630-4. 
  3. ^ Delini-Stula, A.; Fischbach, R.; Gnirss, F.; Bures, E.; Pöldinger, W. (1985). "Early experience with CGP 4718 A (Sercloremine), a new selective and reversible MAO-A and 5-HT-uptake inhibitor, in the treatment of depressive patients". Drug Development Research 6 (4): 371–384. ISSN 0272-4391. doi:10.1002/ddr.430060409. 



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