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Serous carcinoma

Serous carcinoma
File:Serous carcinoma cytology.jpg
Micrograph of serous carcinoma.
Classification and external resources
NCI Serous carcinoma
Patient UK Serous carcinoma

In pathology, serous carcinoma is an epithelial malignancy (carcinoma) that arises from the lining of a cavity that produces a serum-like fluid (a serous cavity).

Serous lined cavities include the peritoneum, pericardium and pleural space and tunica vaginalis.[1]

Cytologic features

Cytologic features of serous carcinoma are:[citation needed]

  • Marked intragroup nuclear pleomorphism.
  • Macronucleoli.
  • "Knobby" group borders (in large groups).
  • Hydropic vacuoles.

Symptoms of serous carcinoma may include:[2]

  • Discomfort/pain or bloating in abdomen
  • Frequent urination
  • Weight loss

Differential diagnosis

The differential diagnosis of serous carcinoma not otherwise specified includes:

There has been the suggestion that the above diagnoses really represent one entity.[3]

See also


  1. ^ Serous Membranes & Cavities Lecture. Veterinary Anatomy Web Site. University of Minnesota. URL: Accessed on: February 6, 2010.
  2. ^ "Serous Carcinoma: A Detailed Guide". The CG Law Firm. Retrieved 26 October 2014. 
  3. ^ Dubeau, L. (Dec 2008). "The cell of origin of ovarian epithelial tumours.". Lancet Oncol 9 (12): 1191–7. PMID 19038766. doi:10.1016/S1470-2045(08)70308-5.