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Simtuzumab

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Simtuzumab?
Monoclonal antibody
Type Whole antibody
Source Humanized
Target LOXL2
Clinical data
Identifiers
1318075-13-6
None
Chemical data
Formula C6558H10134N1736O2037S50
147.5 kDa

Simtuzumab (INN; formerly GS 6624) is a humanized monoclonal antibody designed for the treatment of fibrosis.[1] It binds to LOXL2 and acts as an immunomodulator.[2]

References

  1. ^ Statement On A Nonproprietary Name Adopted By The USAN Council - Simtuzumab, American Medical Association.
  2. ^ World Health Organization (2012). "International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 107" (PDF). WHO Drug Information 26 (2). 


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