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Sulfadiazine

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Sulfadiazine
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Systematic (IUPAC) name
4-amino-N-pyrimidin- 2-yl-benzenesulfonamide
Clinical data
AHFS/Drugs.com monograph
MedlinePlus a682130
  •  ?
  • (Prescription only)
Topical cream, oral
Pharmacokinetic data
Bioavailability ?
Metabolism ?
Half-life ?
Excretion ?
Identifiers
68-35-9 7pxY
J01EC02 QJ01EQ10
PubChem CID 5215
DrugBank DB00359 7pxN
ChemSpider 5026 7pxN
UNII 0N7609K889 7pxN
KEGG D00587 7pxY
ChEMBL CHEMBL439 7pxN
Chemical data
Formula C10H10N4O2S
250.278 g/mol
 14pxN (what is this?)  (verify)

Sulfadiazine is a sulfonamide antibiotic.

It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.[1]

Medical uses

It eliminates bacteria that cause infections by stopping the production of folate inside the bacterial cell, and is commonly used to treat urinary tract infections.

In combination, sulfadiazine and pyrimethamine, can be used to treat toxoplasmosis, a disease caused by Toxoplasma gondii.

Side effects

Side effects reported for sulfadiazine include: nausea, upset stomach, loss of appetite, and dizziness.

Brand names

Lantrisul; Neotrizine; Sulfa-Triple #2; Sulfadiazine; Sulfaloid; Sulfonamides Duplex; Sulfose; Terfonyl; Triple Sulfa; Triple Sulfas; Triple Sulfoid

See also

References

  1. "WHO Model List of EssentialMedicines" (PDF). World Health Organization. October 2013. Retrieved 22 April 2014. 

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