Open Access Articles- Top Results for Suproclone


Systematic (IUPAC) name
[6-(7-chloro-1,8-naphthyridin-2-yl)-5-oxo-3,7- dihydro-2H-[1,4]dithiino[2,3-c]pyrrol-7-yl]-4-propanoylpiperazine-1-carboxylate
Clinical data
77590-92-2 7pxN
PubChem CID 53696
ChemSpider 48481 7pxY
UNII J4AM5D708G 7pxY
KEGG D05975 7pxY
Chemical data
Formula C22H22ClN5O4S2
520.024 g/mol
 14pxN (what is this?)  (verify)

Suproclone is a sedative and anxiolytic drug in the cyclopyrrolone family of drugs, developed by the French pharmaceutical company Rhône-Poulenc.[1] Other cyclopyrrolone drugs include zopiclone, pagoclone and suriclone.

Suproclone is very similar in structure to the related drug suriclone, but little information has been published about it specifically. However it can be expected that the mechanism of action by which suproclone produces its sedative and anxiolytic effects is by modulating benzodiazepine receptors (resulting in an increased response to endogenous GABA), in a similar manner to other drugs of this class.[2][3]


  1. ^ "suproclone". Retrieved 24 August 2009. 
  2. ^ Colin R. Gardner. Pharmacological profiles in vivo of benzodiazepine receptor ligands. Drug Development Research 1988. 12(1):1-28.
  3. ^ Ian L. Martin, Adam Doble, David J. Nutt. Calming the Brain: Benzodiazepines and Related Drugs from Laboratory to Clinic. Informa Healthcare (October 24, 2003). ISBN 1-84184-052-1

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