Open Access Articles- Top Results for TAS2R1


SymbolsTAS2R1 ; T2R1; TRB7
External IDsOMIM604796 MGI2681253 HomoloGene10480 IUPHAR: 659 GeneCards: TAS2R1 Gene
RNA expression pattern
File:PBB GE TAS2R1 221324 at tn.png
More reference expression data
RefSeq (mRNA)NM_019599NM_020503
RefSeq (protein)NP_062545NP_065249
Location (UCSC)Chr 5:
9.63 – 9.71 Mb
Chr 15:
32.18 – 32.18 Mb
PubMed search[1][2]

Taste receptor type 2 member 1 is a protein that in humans is encoded by the TAS2R1 gene.[1][2][3]


This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. This intronless taste receptor gene encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is mapped to chromosome 5p15, the location of a genetic locus (PROP) that controls the detection of the bitter compound 6-n-propyl-2-thiouracil.[3]

See also


  1. ^ Adler E, Hoon MA, Mueller KL, Chandrashekar J, Ryba NJ, Zuker CS (Apr 2000). "A novel family of mammalian taste receptors". Cell 100 (6): 693–702. PMID 10761934. doi:10.1016/S0092-8674(00)80705-9. 
  2. ^ Matsunami H, Montmayeur JP, Buck LB (Apr 2000). "A family of candidate taste receptors in human and mouse". Nature 404 (6778): 601–4. PMID 10766242. doi:10.1038/35007072. 
  3. ^ a b "Entrez Gene: TAS2R1 taste receptor, type 2, member 1". 

Further reading


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