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TAS2R13

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Identifiers
SymbolsTAS2R13 ; T2R13; TRB3
External IDsOMIM604792 MGI2681259 HomoloGene41542 IUPHAR: 667 GeneCards: TAS2R13 Gene
Orthologs
SpeciesHumanMouse
Entrez50838387349
EnsemblENSG00000212128ENSMUSG00000071150
UniProtQ9NYV9Q7M720
RefSeq (mRNA)NM_023920NM_207024
RefSeq (protein)NP_076409NP_996907
Location (UCSC)Chr 12:
11.06 – 11.06 Mb
Chr 6:
132.7 – 132.7 Mb
PubMed search[1][2]

Taste receptor type 2 member 13 is a protein that in humans is encoded by the TAS2R13 gene.[1][2][3]

Function

This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13.[3]

See also

References

  1. ^ Adler E, Hoon MA, Mueller KL, Chandrashekar J, Ryba NJ, Zuker CS (Apr 2000). "A novel family of mammalian taste receptors". Cell 100 (6): 693–702. PMID 10761934. doi:10.1016/S0092-8674(00)80705-9. 
  2. ^ Matsunami H, Montmayeur JP, Buck LB (Apr 2000). "A family of candidate taste receptors in human and mouse". Nature 404 (6778): 601–4. PMID 10766242. doi:10.1038/35007072. 
  3. ^ a b "Entrez Gene: TAS2R13 taste receptor, type 2, member 13". 

Further reading

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