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Open Access Articles- Top Results for TB-21007

TB-21007

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TB-21007
Skeletal formula
Space-filling model
Systematic (IUPAC) name
6,6-dimethyl-3-(2-hydroxyethyl)thio-1-(thiazol-2-yl)-6,7-dihydro-2-benzothiophen-4(5H)-one
Clinical data
Identifiers
207306-50-1 7pxY
Chemical data
Formula C15H17NO2S3
339.495 g/mol
 14pxY (what is this?)  (verify)

TB-21007 is a nootropic drug which acts as a subtype-selective inverse agonist at the α5 containing GABAA receptors.[1][2]

See also

References

  1. ^ Chambers MS, Atack JR, Bromidge FA et al. (2002). "6,7-Dihydro-2-benzothiophen-4(5H)-ones: a novel class of GABA-A alpha5 receptor inverse agonists". J. Med. Chem. 45 (6): 1176–9. PMID 11881985. doi:10.1021/jm010471b. 
  2. ^ Chambers MS, Atack JR, Broughton HB et al. (2003). "Identification of a novel, selective GABA(A) alpha5 receptor inverse agonist which enhances cognition". J. Med. Chem. 46 (11): 2227–40. PMID 12747794. doi:10.1021/jm020582q. 



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