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TFAP4

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Identifiers
SymbolsTFAP4 ; AP-4; bHLHc41
External IDsOMIM600743 MGI103239 HomoloGene2424 GeneCards: TFAP4 Gene
RNA expression pattern
File:PBB GE TFAP4 205688 at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez702383383
EnsemblENSG00000090447ENSMUSG00000005718
UniProtQ01664Q9JIZ5
RefSeq (mRNA)NM_003223NM_031182
RefSeq (protein)NP_003214NP_112459
Location (UCSC)Chr 16:
4.31 – 4.32 Mb
Chr 16:
4.54 – 4.56 Mb
PubMed search[1][2]

Transcription factor AP-4 (activating enhancer binding protein 4), also known as TFAP4, is a protein which in humans is encoded by the TFAP4 gene.[1]

Function

Transcription factor AP4 is a member of the basic helix-loop-helix (bHLH) transcription factors, which bind to the E-box sequence in the promoters of their target genes. AP-4 has been shown to act both as a repressor and an activator for different target genes.

References

Further reading

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External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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