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Open Access Articles- Top Results for TPK1

TPK1

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Identifiers
SymbolsTPK1 ; HTPK1; PP20; THMD5
External IDsOMIM606370 MGI1352500 HomoloGene6960 ChEMBL: 6155 GeneCards: TPK1 Gene
EC number2.7.6.2
RNA expression pattern
File:PBB GE TPK1 221218 s at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez2701029807
EnsemblENSG00000196511ENSMUSG00000029735
UniProtQ9H3S4Q9R0M5
RefSeq (mRNA)NM_001042482NM_013861
RefSeq (protein)NP_001035947NP_038889
Location (UCSC)Chr 7:
144.45 – 144.84 Mb
Chr 6:
43.35 – 43.67 Mb
PubMed search[1][2]

Thiamin pyrophosphokinase 1 is an enzyme that in humans is encoded by the TPK1 gene.[1][2]

This gene encodes a protein, that exists as a homodimer, which catalyzes the conversion of thiamine to thiamine pyrophosphate. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.[2]

References

  1. ^ Nosaka K, Onozuka M, Kakazu N, Hibi S, Nishimura H, Nishino H, Abe T (May 2001). "Isolation and characterization of a human thiamine pyrophosphokinase cDNA". Biochim Biophys Acta 1517 (2): 293–7. PMID 11342111. doi:10.1016/s0167-4781(00)00247-5. 
  2. ^ a b "Entrez Gene: TPK1 thiamin pyrophosphokinase 1". 

Further reading

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