Open Access Articles- Top Results for Tandamine


Systematic (IUPAC) name
Clinical data
42408-80-0 7pxY
PubChem CID 39187
ChemSpider 35851
UNII 7516K9UGUG 7pxY
Chemical data
Formula C18H26N2S
302.476 g/mol
 14pxY (what is this?)  (verify)

Tandamine is a selective norepinephrine reuptake inhibitor with a tricyclic structure.[1][2][3] It was developed in the 1970s as an antidepressant but was never commercialized.[1][2][3] Tandamine is analogous to pirandamine, which, instead, acts as a selective serotonin reuptake inhibitor (SSRI).[4][5]

See also


  1. ^ a b Lippmann W, Pugsley TA (May 1976). "The effects of tandamine, a new potential antidepressant agent, on biogenic amine uptake mechanisms and related activities". Biochemical Pharmacology 25 (10): 1179–86. PMID 1084746. doi:10.1016/0006-2952(76)90366-X. 
  2. ^ a b Ehsanullah RS, Ghose K, Kirby MJ, Turner P, Witts D (March 1977). "Clinical pharmacological studies of tandamine, a potential antidepressive drug". Psychopharmacology 52 (1): 73–7. PMID 403562. doi:10.1007/BF00426603. 
  3. ^ a b Pugsley TA, Lippmann W (September 1979). "Effect of acute and chronic treatment of tandamine, a new heterocyclic antidepressant, on biogenic amine metabolism and related activities". Naunyn-Schmiedeberg's Archives of Pharmacology 308 (3): 239–47. PMID 503251. doi:10.1007/BF00501388. 
  4. ^ Pugsley T, Lippmann W (May 1976). "Effects of tandamine and pirandamine, new potential antidepressants, on the brain uptake of norepinephrine and 5-hydroxytryptamine and related activities". Psychopharmacology 47 (1): 33–41. PMID 1085452. doi:10.1007/BF00428698. 
  5. ^ Lippmann W, Seethaler K (April 1977). "Effects of tandamine and pirandamine, selective blockers of biogenic amine uptake mechanisms, on gastric acid secretion and ulcer formation in the rat". Life Sciences 20 (8): 1393–400. PMID 853871. doi:10.1016/0024-3205(77)90367-8. 

Lua error in package.lua at line 80: module 'Module:Buffer' not found.