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Open Access Articles- Top Results for Tetrindole

Tetrindole

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Tetrindole
File:Tetrindole skeletal.svg
File:Tetrindole ball-and-stick.png
Systematic (IUPAC) name
2,3,3a,4,5,6-Hexahydro-8-cyclohexyl-1H-pyrazino[3,2,1-j,k]carbazole
Clinical data
Identifiers
 7pxY
None
PubChem CID 160020
ChemSpider 140675 7pxY
ChEBI CHEBI:77799 7pxN
Chemical data
Formula C20H26N2
294.43 g/mol
 14pxN (what is this?)  (verify)

Tetrindole is a drug candidate that functions by inhibiting monoamine oxidase A; it was first synthesized in Moscow in the early 1990s.[1] Tetrindole is similar in its chemical structure to pirazidol, pirlindole, and metralindole.[2]

References

  1. ^ Medvedev, Alexei E.; Alexandra A. Kirkel, Natalia S. Kamyshanskaya, Tatyana A. Moskvitina, Ludmila N. Axenova, Vladimir Z. Gorkin, Natalia I. Andreeva, Svetlana M. Golovina and Mikhail D. Mashkovsky (20 January 1994). "Monoamine oxidase inhibition by novel antidepressant tetrindole". Biochemical Pharmacology 47 (2): 303–308. PMID 8304974. doi:10.1016/0006-2952(94)90021-3. 
  2. ^ Ramsay RR, Gravestock MB. Monoamine oxidases: to inhibit or not to inhibit. Mini Rev Med Chem. 2003 Mar;3(2):129-36. PMID 12570845


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