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Open Access Articles- Top Results for Thecoma

Thecoma

Thecoma
File:Thecoma high mag.jpg
High magnification micrograph of a thecoma. H&E stain.
Classification and external resources
ICD-9 220
ICD-O 8600
NCI Thecoma
Patient UK Thecoma
MeSH D013798

Thecomas or theca cell tumors are benign ovarian neoplasms composed only of theca cells. Histogenetically they are classified as sex cord-stromal tumours.

They are typically estrogen-producing and they occur in older women (mean age 59; 84% after menopause). (They can, however, appear before menopause.[1])

Sixty percent of patients present with abnormal uterine bleeding, and 20% have endometrial carcinoma.

Pathologic features

File:Thecoma low mag.jpg
Low magnification micrograph of a thecoma showing compression of the ovarian cortex (right of image). H&E stain.

Grossly, the tumour is solid and yellow.

Grossly and microscopically, it consists of the ovarian cortex.

Microscopically, the tumour cells have abundant lipid-filled cytoplasm.

References

  1. ^ Okada I, Nakagawa S, Takemura Y et al. (October 2004). "Ovarian thecoma associated in the first trimester of pregnancy". J. Obstet. Gynaecol. Res. 30 (5): 368–71. PMID 15327450. doi:10.1111/j.1447-0756.2004.00212.x. 


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