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Thenalidine

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Thenalidine
File:Thenalidine.svg
Systematic (IUPAC) name
1-Methyl-N-phenyl-N-(2-thienylmethyl)piperidin-4-amine
Clinical data
Identifiers
86-12-4 7pxY
D04AA03 R06AX03
R06AX53 (combinations)
PubChem CID 27901
DrugBank DB04826 7pxY
ChemSpider 25957 7pxN
UNII 6U94N2D00F 7pxY
KEGG D07194 7pxY
Chemical data
Formula C17H22N2S
286.436 g/mol
 14pxN (what is this?)  (verify)

Thenalidine is an antihistamine with anticholinergic properties used as an antipruritic drug.[1] It was withdrawn from the US, Canadian, and UK markets in 1963 due to a risk of neutropenia.[2]

References

  1. ^ Getzler, N. A.; Ereaux, L. P. (1959). "Evaluation of thenalidine tratrate (sandostene) in dermatological disorders". Canadian Medical Association journal 80 (6): 445–448. PMC 1830689. PMID 13629433.  edit
  2. ^ "Thenalidine". DrugBank. 

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