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Open Access Articles- Top Results for Thiopurine

Thiopurine

The thiopurine drugs are purine antimetabolites widely used in the treatment of acute lymphoblastic leukemia, autoimmune disorders (e.g., Crohn's disease, rheumatoid arthritis), and organ transplant recipients.

Metabolism is catalyzed by S-methyltransferase.[1]

See also

References

  1. ^ Sahasranaman S, Howard D, Roy S (August 2008). "Clinical pharmacology and pharmacogenetics of thiopurines". Eur. J. Clin. Pharmacol. 64 (8): 753–67. PMID 18506437. doi:10.1007/s00228-008-0478-6. 

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