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Open Access Articles- Top Results for Tositumomab

Tositumomab

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Tositumomab?
Monoclonal antibody
Type Whole antibody
Source Mouse
Target CD20
Clinical data
Trade names Bexxar
AHFS/Drugs.com monograph
MedlinePlus a609013
Identifiers
192391-48-3 7pxY
V10XA53 (sequential regimen with 131I form)
DrugBank DB00081 7pxY
UNII 0343IGH41U 7pxY
KEGG D08622 7pxY
ChEMBL CHEMBL1201604 7pxN
Chemical data
Formula C6416H9874N1688O1987S44
143859.7 g/mol
 14pxN (what is this?)  (verify)

Tositumomab was a drug that was approved for the treatment of relapsed or chemotherapy/rituxan-refractory Non-Hodgkin lymphoma in 2003.[1] It was sold in the U.S. and Canada under the trade name Bexxar. Sale of the drug was discontinued and marketing approval was withdrawn in February 2014 due to the decline in usage (fewer than 75 patients in 2012) and the existence of other similar drugs.[2][3]

This drug combination was developed by Corixa which was purchased by GlaxoSmithKline) in 2005.[4]

References


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