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Open Access Articles- Top Results for Triclofos

Triclofos

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Triclofos
File:Triclofos-2D-skeletal.svg
File:Triclofos-3D-balls.png
Systematic (IUPAC) name
2,2,2-trichloroethanol dihydrogen phosphate
Clinical data
AHFS/Drugs.com International Drug Names
Identifiers
306-52-5 7pxN 8060-81-9
N05CM07
PubChem CID 5563
ChemSpider 5362 7pxY
UNII J712EO9048 7pxY
ChEMBL CHEMBL1201317 7pxN
Chemical data
Formula C2H4Cl3O4P
229.383 g/mol
 14pxN (what is this?)  (verify)

Triclofos is a sedative drug used rarely for treating insomnia, usually as a second-line treatment after other drugs have failed. Triclofos may cause dependence and should not be withdrawn suddenly. This drug should only be used for the short term relief of severe insomnia and should not be mixed with alcohol or other depressant drugs. Patients should not drive or use machinery after taking triclofos.

Triclofos is a prodrug which is metabolised in the liver into the active drug trichloroethanol. This delayed action means that the half-life of triclofos is fairly long and it may cause drowsiness the next day. Trichloroethanol may cause liver damage and triclofos should not be used for extended periods.

Side effects

Side effects may include: headache, rash, dizziness, flatulence, confusion, nightmares, dependence, diarrhoea, constipation, nausea, vomiting, abdominal pain, and ataxia.

References



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