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Open Access Articles- Top Results for Tuaminoheptane

Tuaminoheptane

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Tuaminoheptane
Skeletal formula of tuaminoheptane
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IUPAC name
Heptan-2-amine[1]
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ATC code R01AA11

R01AB08 (combinations)
635676, 4652352 R, 1719086 S
123-82-0 7pxY
6240-90-0 R 7pxY
44745-29-1 S 7pxY
ChEMBL ChEMBL123693 7pxY
ChemSpider 5401 7pxY
5360930 R 7pxY
2016267 S 7pxY
EC number 204-655-522
Jmol-3D images Image
KEGG D07371 7pxY
MeSH tuamine
PubChem Template:Chembox PubChem/formatTemplate:Chembox PubChem/formatTemplate:Chembox PubChem/format
RTECS number MQ5425000
UN number 1993
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C7H17N
Molar mass Lua error in Module:Math at line 495: attempt to index field 'ParserFunctions' (a nil value). g·mol−1
Appearance Colourless liquid
Density 0.766 g/mL
Boiling point Script error: No such module "convert".
log P 2.429
1.418–1.419
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GHS pictograms The flame pictogram in the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) The exclamation-mark pictogram in the Globally Harmonized System of Classification and Labelling of Chemicals (GHS)
GHS signal word WARNING
H226, H315, H319, H335
P261, P305+351+338
EU classification Irritant Xi
R-phrases R10, R36/37/38
S-phrases S26, S36
Flash point Script error: No such module "convert".
130 mg kg−1 (subcutaneous, rat)
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Related alkanamines
Related compounds
Octamoxin
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Tuaminoheptane (or tuamine) is a nasal decongestant drug which is a sympathomimetic stimulant and vasoconstrictor.[2] However, it can cause skin irritation,[3] which limits its usefulness as a nasal decongestant. Oral preparations were once available, but are no longer produced. Side effects associated with the use of tuaminoheptane can include shortness of breath, tachycardia and hypertension.

Tuaminoheptane is on the 2011 list of prohibited substances published by the World Anti-Doping Agency.

See also

References

  1. ^ "tuamine - Compound Summary". USA: National Center for Biotechnology Information. 25 March 2005. Identification and Related Records. Retrieved 31 May 2012. 
  2. ^ Delicado, E. G.; Fideu, M. D.; Miras-Portugal, M. T.; Pourrias, B.; Aunis, D. (1990). "Effect of tuamine, heptaminol and two analogues on uptake and release of catecholamines in cultured chromaffin cells". Biochemical Pharmacology 40 (4): 821–825. PMID 2386550. doi:10.1016/0006-2952(90)90322-C. 
  3. ^ Raoux, M.; Colomban, C.; Delmas, P.; Crest, M. (2007). "The amine-containing cutaneous irritant heptylamine inhibits the volume-regulated anion channel and mobilizes intracellular calcium in normal human epidermal keratinocytes". Molecular Pharmacology 71 (6): 1685–1694. PMID 17384225. doi:10.1124/mol.106.033324. 

External links