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Open Access Articles- Top Results for Tyrosine-protein kinase BLK

Tyrosine-protein kinase BLK

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Identifiers
SymbolsBLK ; MODY11
External IDsOMIM191305 MGI88169 HomoloGene1297 IUPHAR: 1940 ChEMBL: 2250 GeneCards: BLK Gene
EC number2.7.10.2
RNA expression pattern
File:PBB GE BLK 206255 at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez64012143
EnsemblENSG00000136573ENSMUSG00000014453
UniProtP51451P16277
RefSeq (mRNA)NM_001715NM_007549
RefSeq (protein)NP_001706NP_031575
Location (UCSC)Chr 8:
11.35 – 11.42 Mb
Chr 14:
63.37 – 63.42 Mb
PubMed search[1][2]

Tyrosine-protein kinase BLK also known as B lymphocyte kinase is an enzyme that in humans is encoded by the BLK gene.[1][2]


Interactions

The tyrosine-protein kinase BLK has been shown to interact with UBE3A.[3]

References

  1. ^ Drebin JA, Hartzell SW, Griffin C, Campbell MJ, Niederhuber JE (Mar 1995). "Molecular cloning and chromosomal localization of the human homologue of a B-lymphocyte specific protein tyrosine kinase (blk)". Oncogene 10 (3): 477–86. PMID 7845672. 
  2. ^ "Entrez Gene: BLK B lymphoid tyrosine kinase". 
  3. ^ Oda H, Kumar S, Howley PM (August 1999). "Regulation of the Src family tyrosine kinase Blk through E6AP-mediated ubiquitination". Proc. Natl. Acad. Sci. U.S.A. 96 (17): 9557–62. PMC 22247. PMID 10449731. doi:10.1073/pnas.96.17.9557. 

Further reading

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