The University of South Carolina Union is a public university with its main campus in Columbia, South Carolina and a branch campus in Laurens. It is one of the four regional USC campuses which make up Palmetto College. USC Union is currently a Southern Association of Colleges and Schools accredited two-year school in the USC System. Between 500 and 600 students attend the University at one of its two campuses.
In the 1960s, the citizens of Union formed the Union County Commission for Higher Education to attract a college to their area. The University of South Carolina sought to expand its reach throughout the state and agreed to build an extension campus in Union. Classes began at the campus in 1965 with an initial enrollment of 51 students. The campus currently includes four buildings in downtown Union with a branch campus in Laurens at the Laurens County Higher Education Center.